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Brachytherapy is an efficient treatment for numerous cancer diseases. To support this, the Cancer News regularly inform about related studies and articles as well as cancer demographics. Subscribe to our newsletter to receive the latest news first:
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December 23, 2019

Analysis of local recurrence causes in uveal melanoma patients treated with 125I brachytherapy – a single institution study

Purpose: Uveal melanoma is the most frequent intraocular tumour in adults [1,2]. It originates from pigment cells of the iris, the ciliary body and choroid undergoing tumour transformation [3]. The prevalence of uveal melanoma depends on race, sex and latitude...

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August 29, 2019

Complications and adverse events of plaque brachytherapy for ocular melanoma

Purpose: In 2016, an estimated 2,810 new cases of primary intraocular tumors were diagnosed, having led to 280 deaths nationwide [1]. The most common primary intraocular tumor is uveal melanoma, also known as ocular melanoma...

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February 28, 2019

Current state of interventional radiotherapy (brachytherapy) education in Italy: results of the INTERACTS survey

Purpose: Rapid evolution and improvement of technology in radiation oncology and the complexity of each area of radiotherapy (RT) practice determined the need for an adequate and flexible practical training system. In the field of interventional radiotherapy (brachytherapy – BT), a decline in BT utilization was detected in the 1990’s, essentially due to technological improvement of external beam RT...

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February 13, 2019

Personalized re-treatment strategy for uveal melanoma local recurrences after interventional radiotherapy (brachytherapy): single institution experience and systematic literature review

Purpose: Episcleral plaque radiotherapy is an effective method of controlling uveal melanoma locally as confirmed by long-term results [1]. Unfortunately, failure of the radioactive plaque to control tumor growth is occasionally observed [2]. Data published in a review by Chang presents local failure rates following various forms of conservative treatments for uveal melanoma [3]...

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December 11, 2018

Surface dose rate from a flat 106Ru/106Rh episcleral plaque measured with a planar windowless extrapolation chamber and un-laminated EBT3 film

In this work, a planar extrapolation chamber without an entrance window was used to measure surface dose rate to water from a flat 106Ru/106Rh plaque manufactured by Eckert & Ziegler BEBIG...

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November 26, 2018

Outcomes of I-125 brachytherapy for uveal melanomas depending on irradiation dose applied to the tumor apex – a single institution study

Purpose: The aim of the study was an evaluation of I-125 brachytherapy patients with uveal melanoma with special consideration for the relationship of the treatment results and the irradiation dose applied to the tumor apex...

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May 18, 2018

Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma

Purpose: To describe the vascular changes of circumscribed choroidal hemangioma (CCH) after ruthenium-106 brachytherapy using optical coherence tomography angiography (angio-OCT)...

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April 30, 2018

Ruthenium brachytherapy for intraocular growth of a conjunctival squamous cell carcinoma: a case report

Abstract: The aim of this study is to report the use of ruthenium brachytherapy as an adjunctive treatment in the management of an intraocular extension of the conjunctival squamous cell carcinoma (SCC). In 2013, a 73-year-old man presented with a tumor blocking the angle and infiltrating corneal endothelium. The patient was treated with iridectomy, and after one month, ruthenium brachytherapy...

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April 30, 2018

Visual outcome after posterior uveal melanoma episcleral brachytherapy including radiobiological doses

Purpose: Uveal melanoma is the most frequent primary malignant intraocular tumor occurring in adults, with an annual age-adjusted incidence of 5.1 per million [1]. Approximately, 90% of all uveal melanomas’ develops in the choroid, 7% in the ciliary body, and 3% in the iris [1]. In the past, uveal melanoma was treated with enucleation, but plaque brachytherapy...

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March 30, 2018

Radiation Therapy Research: A Global Analysis 2001-2015

Radiation therapy is a core modality of cancer treatment; however, concerns have been expressed regarding its underutilization and its lack of prioritization as a research domain relative to other cancer treatment modalities, despite its rapid technical evolution...

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February 13, 2018

Retina dose as a predictor for visual acuity loss in 106Ru eye plaque brachytherapy of uveal melanomas

Background and purpose: To evaluate the retina dose as a risk factor associated with loss of visual acuity (VA) in 106Ru plaque brachytherapy...

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January 18, 2018

Quality of training in radiation oncology in Germany: where do we stand?

Purpose: To evaluate the current situation of young radiation oncologists in Germany with regard to the contents and quality of training and level of knowledge, as well as their working conditions and professional satisfaction...

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December 21, 2017

Ruthenium brachytherapy for uveal melanomas: Factors affecting the development of radiation complications

Purpose: To investigate how treatment complications are related to dosimetric parameters after ruthenium-106 brachytherapy for uveal melanoma, in a large, clinically homogeneous population...

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December 15, 2017

Use of Ruthenium-106 Brachytherapy for Iris Melanoma: The Scottish Experience

Purpose: To analyse long-term outcomes of ruthenium-106 (106Ru) plaque brachytherapy for the treatment of iris melanoma...

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November 09, 2017

Ruthenium-106 brachytherapy for iris and iridociliary melanomas

Background and purpose: To evaluate ruthenium-106 (Ru106) brachytherapy as eye-conserving treatment of iris melanomas (IMs) and iridociliary melanomas (ICMs)...

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October 05, 2017

Choroidal melanoma: A short review with an Indian perspective

Choroidal melanoma (CM), the most common intraocular tumor in adults, is still a rarity in Asia. Having a high propensity for metastasis with a poor survival, recognizing it early is essential. Although it has typical clinical features, there are instances of simulating lesions. Fine-needle aspiration biopsy can be a valuable tool not only to confirm our clinical suspicion but also aid in prognosticating it...

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July 28, 2017

Brachytherapy patient safety events in an academic radiation medicine program

Purpose: To describe the incidence and type of brachytherapy patient safety events over 10 years in an academic brachytherapy program...

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May 29, 2017

Pattern of Local Recurrence After I-125 Episcleral Brachytherapy for Uveal Melanoma in a Spanish Referral Ocular Oncology Unit

Purpose: To describe the time, frequency, and clinical characteristics of treatment failure after I-125 brachytherapy in patients with uveal melanoma treated and followed in a Spanish referral ocular oncology unit...

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March 09, 2016

Analysis of Secondary Primary Tumors In Patients With Uveal Melanoma

Uveal melanoma (UM) is the most common malignant tumor of the eye in adults. More than half of the patients are long-term survivors. It is well established for other malignancies that cancer survivors are especially prone to developing independent second primary neoplasms...

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July 15, 2015

Non-ocular primary malignancies in patients with uveal melanoma: the Liverpool experience

Aim: To identify the prevalence of self-reported non-ocular primary malignancies in patients at the time of diagnosis with uveal melanoma (UM) and to describe the cohort’s characteristics...
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June 10, 2015

Clinical presentation and survival of retinoblastoma in Indian children

Objective: To study the clinical presentation and survival among Indian children with retinoblastoma (RB) and to determine factors predictive of poor outcome...
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May 15, 2015

Ruthenium-106 plaque brachytherapy for uveal melanoma Background

To report on local tumour control, eye preservation and visual outcome after ruthenium-106 brachytherapy for uveal melanoma...
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December 24, 2013

The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma

PURPOSE: To present the American Brachytherapy Society (ABS) guidelines for plaque brachytherapy of choroidal melanoma and retinoblastoma...

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March 20, 2012

Tumor control, eye preservation, and visual outcomes of ruthenium plaque brachytherapy for choroidal melanoma

PURPOSE: To evaluate outcomes in patients with posterior choroidal melanoma treated with ruthenium (106Ru) brachytherapy...

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